Assay
Age
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Western blot
Postnatal
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H2ax H2A.X variant histone (Synonyms: gammaH2ax, H2afx, H2A.X, Hist5-2ax) | |
Results | Reference |
1 | J:264269 Azimi M, Le TT, Brown NL, Presenilin gene function and Notch signaling feedback regulation in the developing mouse lens. Differentiation. 2018 Jul - Aug;102:40-52 |
1 | J:252554 Bianchi FT, Tocco C, Pallavicini G, Liu Y, Verni F, Merigliano C, Bonaccorsi S, El-Assawy N, Priano L, Gai M, Berto GE, Chiotto AM, Sgro F, Caramello A, Tasca L, Ala U, Neri F, Oliviero S, Mauro A, Geley S, Gatti M, Di Cunto F, Citron Kinase Deficiency Leads to Chromosomal Instability and TP53-Sensitive Microcephaly. Cell Rep. 2017 Feb 14;18(7):1674-1686 |
1 | J:274697 Celaya AM, Sanchez-Perez I, Bermudez-Munoz JM, Rodriguez-de la Rosa L, Pintado-Berninches L, Perona R, Murillo-Cuesta S, Varela-Nieto I, Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss. Elife. 2019 Apr 2;8:e39159 |
1 | J:317403 De Clercq S, Gembarska A, Denecker G, Maetens M, Naessens M, Haigh K, Haigh JJ, Marine JC, Widespread overexpression of epitope-tagged Mdm4 does not accelerate tumor formation in vivo. Mol Cell Biol. 2010 Nov;30(22):5394-405 |
1 | J:325094 Guan Y, Lin H, Leu NA, Ruthel G, Fuchs SY, Busino L, Luo M, Wang PJ, SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination. Nucleic Acids Res. 2022 May 20;50(9):5129-5144 |
1 | J:225041 Hasegawa K, Sin HS, Maezawa S, Broering TJ, Kartashov AV, Alavattam KG, Ichijima Y, Zhang F, Bacon WC, Greis KD, Andreassen PR, Barski A, Namekawa SH, SCML2 establishes the male germline epigenome through regulation of histone H2A ubiquitination. Dev Cell. 2015 Mar 9;32(5):574-88 |
1 | J:306320 Ho UY, Feng CA, Yeap YY, Bain AL, Wei Z, Shohayeb B, Reichelt ME, Homer H, Khanna KK, Bowles J, Ng DCH, WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis. Commun Biol. 2021 May 31;4(1):645 |
1 | J:244859 Liu W, Wang F, Xu Q, Shi J, Zhang X, Lu X, Zhao ZA, Gao Z, Ma H, Duan E, Gao F, Gao S, Yi Z, Li L, BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis. Nat Commun. 2017 Jan 27;8:14182 |
1* | J:264258 Miyamoto Y, Whiley PAF, Goh HY, Wong C, Higgins G, Tachibana T, McMenamin PG, Mayne L, Loveland KL, The STK35 locus contributes to normal gametogenesis and encodes a lncRNA responsive to oxidative stress. Biol Open. 2018 Aug 6;7(8):bio032631 |
1* | J:138760 Reynard LN, Turner JM, Cocquet J, Mahadevaiah SK, Toure A, Hoog C, Burgoyne PS, Expression analysis of the mouse multi-copy X-linked gene Xlr-related, meiosis-regulated (Xmr), reveals that Xmr encodes a spermatid-expressed cytoplasmic protein, SLX/XMR. Biol Reprod. 2007 Aug;77(2):329-35 |
1 | J:331366 Song Y, Chen M, Zhang Y, Li J, Liu B, Li N, Chen M, Qiao M, Wang N, Cao Y, Lu S, Chen J, Sun W, Gao F, Wang H, Loss of circSRY reduces gammaH2AX level in germ cells and impairs mouse spermatogenesis. Life Sci Alliance. 2023 Feb;6(2) |
1* | J:173957 Tsutsumi M, Kogo H, Kowa-Sugiyama H, Inagaki H, Ohye T, Kurahashi H, Characterization of a Novel Mouse Gene Encoding an SYCP3-Like Protein That Relocalizes from the XY Body to the Nucleolus During Prophase of Male Meiosis I. Biol Reprod. 2011 Jul;85(1):165-71 |
1* | J:239876 Xu Q, Wang F, Xiang Y, Zhang X, Zhao ZA, Gao Z, Liu W, Lu X, Liu Y, Yu XJ, Wang H, Huang J, Yi Z, Gao S, Li L, Maternal BCAS2 protects genomic integrity in mouse early embryonic development. Development. 2015 Nov 15;142(22):3943-53 |
1 | J:326486 Zhang D, Liu C, Li H, Jiao J, Deficiency of STING Signaling in Embryonic Cerebral Cortex Leads to Neurogenic Abnormalities and Autistic-Like Behaviors. Adv Sci (Weinh). 2020 Dec;7(23):2002117 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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